Label free localization of nanoparticles in live cancer cells using spectroscopic microscopy

Gold nanoparticles (GNPs) have become essential tools used in nanobiotechnology due to their tunable plasmonic properties and low toxicity in biological samples. Among the available approaches for imaging GNPs internalized by cells, hyperspectral techniques stand out due to their ability to simultan...

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Veröffentlicht in:	Nanoscale 2018-10, Vol.1 (4), p.19125-1913
Hauptverfasser:	Spicer, Graham L. C, Almassalha, Luay, Martinez, Ignacio A, Ellis, Ronald, Chandler, John E, Gladstein, Scott, Zhang, Di, Nguyen, The-Quyen, Feder, Seth, Subramanian, Hariharan, de la Rica, Roberto, Thompson, Sebastian A, Backman, Vadim
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorption spectra Backscattering Biological properties Cancer Cellular structure Electron beams Electron bombardment Gold Gold - chemistry Gold - pharmacology HeLa Cells Humans Hyperspectral imaging Localization Materials Testing Metal Nanoparticles - chemistry Nanoparticles Nanotechnology Neoplasms - diagnostic imaging Neoplasms - metabolism Principal components analysis Temporal resolution Toxicity White light
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