Multi-gram scale synthesis of a bleomycin (BLM) carbohydrate moiety: exploring the antitumor beneficial effect of BLM disaccharide attached to 10-hydroxycamptothecine (10-HCPT)Electronic supplementary information (ESI) available. See DOI: 10.1039/c8nj06191b

The "tumor-seeking" role of bleomycin (BLM) disaccharide has been demonstrated to serve as a promising tool for cancer diagnosis and a potential ligand for targeted therapy. However, these practical applications are often hampered by the lack of BLM disaccharide. Herein, an efficient multi...

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Hauptverfasser: Li, MaoLin, Huang, Weiping, Jiang, Zhilin, Shi, Yonghui, Yuan, Sisi, Fu, Kaishuo, Chen, YongJun, Zhou, Li, Zhou, Wen
Format: Artikel
Sprache:eng
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