Interaction of a gold(i) dicarbene anticancer drug with human telomeric DNA G-quadruplex: solution and computationally aided X-ray diffraction analysisElectronic supplementary information (ESI) available. See DOI: 10.1039/c8dt03607a

The bis carbene gold( i ) complex [Au(1-butyl-3-methyl-2-ylidene) 2 ]PF 6 , ([Au(NHC) 2 ]PF 6 hereafter), holds remarkable interest as a perspective anticancer agent. The compound is stable under physiological like conditions: its original structure is retained even in the presence of excess glutath...

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Hauptverfasser: Guarra, Federica, Marzo, Tiziano, Ferraroni, Marta, Papi, Francesco, Bazzicalupi, Carla, Gratteri, Paola, Pescitelli, Gennaro, Messori, Luigi, Biver, Tarita, Gabbiani, Chiara
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Sprache:eng
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