Polyethyleneimine methylenecarboxylate: a macromolecular DTPA analogue to chelate plutonium(iv)Electronic supplementary information (ESI) available. See DOI: 10.1039/c8cc05206a

Polyethyleneimine methylenecarboxylate: a macromolecular DTPA analogue to chelate plutonium(iv)Electronic supplementary information (ESI) available. See DOI: 10.1039/c8cc05206a

Up until now, molecular chelating agents, such as diethylenetriamine pentaacetic acid (DTPA), have been the standard method for actinide human decorporation. Mainly active in blood serum, their distribution within the body is thus limited. To treat a wider range of organs affected by plutonium conta...

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Hauptverfasser: Lahrouch, Florian, Siberchicot, Bruno, Leost, Laurane, Aupiais, Jean, Rossberg, André, Hennig, Christoph, Den Auwer, Christophe, Di Giorgio, Christophe
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container_issue 83
container_start_page 1175
container_title
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creator Lahrouch, Florian
Siberchicot, Bruno
Leost, Laurane
Aupiais, Jean
Rossberg, André
Hennig, Christoph
Den Auwer, Christophe
Di Giorgio, Christophe
description Up until now, molecular chelating agents, such as diethylenetriamine pentaacetic acid (DTPA), have been the standard method for actinide human decorporation. Mainly active in blood serum, their distribution within the body is thus limited. To treat a wider range of organs affected by plutonium contamination, a potential new class of macromolecular decorporation agents is being studied. Polyethyleneimine methylenecarboxylate (PEI-MC) is one such example. It is being considered here because of its capacity for targeting the liver and bones. Polyethyleneimine methylenecarboxylate (PEI-MC) is explored as a possible new class of macromolecular decorporation agents in case of plutonium contamination.
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title Polyethyleneimine methylenecarboxylate: a macromolecular DTPA analogue to chelate plutonium(iv)Electronic supplementary information (ESI) available. See DOI: 10.1039/c8cc05206a
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