Functional human 3D microvascular networks on a chip to study the procoagulant effects of ambient fine particulate matter

Exposure to ambient fine particulate matter (FPM) has been thought to be associated with cardiovascular disease. However, the pathogenesis remains largely unknown. Animal models have been widely used in toxicological research, but species difference makes it impossible to directly translate discover...

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Veröffentlicht in:	RSC advances 2017-01, Vol.7 (88), p.5618-56116
Hauptverfasser:	Li, Yan, Pi, Qing-Meng, Wang, Peng-Cheng, Liu, Lie-Ju, Han, Zheng-Gang, Shao, Yang, Zhai, Ying, Zuo, Zheng-Yu, Gong, Zhi-Yong, Yang, Xu, Wu, Yang
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood flow Blood vessels Cardiovascular disease Computational fluid dynamics Computer simulation Endothelial cells Endothelium Fluid flow Human behavior Nutrients Pathogenesis Physiological responses Physiology Three dimensional models Thrombosis Toxicity
Online-Zugang:	Volltext
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