Synthesis of 4-substituted pyrazole-3,5-diamines Suzuki-Miyaura coupling and iron-catalyzed reduction

A general and efficient synthesis of 4-substituted-1 H -pyrazole-3,5-diamines was developed to access derivatives with an aryl, heteroaryl, or styryl group, which are otherwise relatively difficult to prepare. The first step is based on the Suzuki-Miyaura cross-coupling reaction utilizing the XPhos...

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Veröffentlicht in:	Organic & biomolecular chemistry 2017-12, Vol.15 (48), p.12-1211
Hauptverfasser:	Tomanová, Monika, Jedinák, Lukáš, Koša, Jan, Kvapil, Lubomír, Hradil, Pavel, Canka, Petr
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