Construction of tetrahydropyranoquinoline derivatives an asymmetric organocatalytic aza-Michael-IED/HAD cascade reaction

Chiral functionalized tetrahydroquinolines and pyranoquinolines with multiple stereogenic centres have emerged as attractive structures for derivatizing bioactive complex molecules. Herein, we develop a novel, facile organocatalytic asymmetric aza-Michael-IED/HAD cascade reaction of ( E )-ethyl 4-(2...

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Veröffentlicht in:	Organic & biomolecular chemistry 2017-11, Vol.15 (45), p.963-9637
Hauptverfasser:	Dai, Lu, Hou, Yuxuan, Zhang, Lvye, Chen, Zhangtao, Zeng, Xiaofei, Zhong, Guofu
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