Enantioselective [4 + 1] cycloaddition of ortho-quinone methides and bromomalonates under phase-transfer catalysisElectronic supplementary information (ESI) available. CCDC 1531397. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c7ob00484b

An enantioselective [4 + 1] cycloaddition reaction of ortho -quinone methides and bromomalonates using a quinine and BINOL derived phase-transfer catalyst is described. With high yields and enantioselectivities, the method provided a variety of optically active dihydrobenzofurans, which represent a...

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Hauptverfasser: Lian, Xiao-Lei, Adili, Alafate, Liu, Bin, Tao, Zhong-Lin, Han, Zhi-Yong
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Adili, Alafate
Liu, Bin
Tao, Zhong-Lin
Han, Zhi-Yong
description An enantioselective [4 + 1] cycloaddition reaction of ortho -quinone methides and bromomalonates using a quinine and BINOL derived phase-transfer catalyst is described. With high yields and enantioselectivities, the method provided a variety of optically active dihydrobenzofurans, which represent a valuable structural motif present in numerous naturally occurring and biologically active molecules. An enantioselective [4 + 1] cycloaddition reaction of ortho -quinone methides and bromomalonates using a quinine and BINOL derived phase-transfer catalyst is described.
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title Enantioselective [4 + 1] cycloaddition of ortho-quinone methides and bromomalonates under phase-transfer catalysisElectronic supplementary information (ESI) available. CCDC 1531397. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c7ob00484b
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