Lectin-gated and glycan functionalized mesoporous silica nanocontainers for targeting cancer cells overexpressing Lewis X antigenElectronic supplementary information (ESI) available: PXRD patterns of the as-synthesized MSNs and extracted MSNs; TEM images of MSNs and solid S3; N2 adsorption-desorption isotherms for MSNs and pore size distribution; and the release profile of ATTO 430LS dye from solid S3 in cellular medium. See DOI: 10.1039/c7nr06415b

Lectin-gated and glycan functionalized mesoporous silica nanocontainers for targeting cancer cells overexpressing Lewis X antigenElectronic supplementary information (ESI) available: PXRD patterns of the as-synthesized MSNs and extracted MSNs; TEM images of MSNs and solid S3; N2 adsorption-desorption isotherms for MSNs and pore size distribution; and the release profile of ATTO 430LS dye from solid S3 in cellular medium. See DOI: 10.1039/c7nr06415b

Gated mesoporous silica nanoparticles can deliver payload upon the application of a predefined stimulus, and therefore are promising drug delivery systems. Despite their important role, relatively low emphasis has been placed on the design of gating systems that actively target carbohydrate tumor ce...

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Hauptverfasser: Bhat, R, García, I, Aznar, E, Arnaiz, B, Martínez-Bisbal, M. C, Liz-Marzán, L. M, Penadés, S, Martínez-Máñez, R
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Sprache:eng
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