Closed-loop feedback control for microfluidic systems through automated capacitive fluid height sensingElectronic supplementary information (ESI) available. See DOI: 10.1039/c7lc01223c

Closed-loop feedback control for microfluidic systems through automated capacitive fluid height sensingElectronic supplementary information (ESI) available. See DOI: 10.1039/c7lc01223c

Precise fluid height sensing in open-channel microfluidics has long been a desirable feature for a wide range of applications. However, performing accurate measurements of the fluid level in small-scale reservoirs (

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Hauptverfasser: Soenksen, L. R, Kassis, T, Noh, M, Griffith, L. G, Trumper, D. L
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creator Soenksen, L. R
Kassis, T
Noh, M
Griffith, L. G
Trumper, D. L
description Precise fluid height sensing in open-channel microfluidics has long been a desirable feature for a wide range of applications. However, performing accurate measurements of the fluid level in small-scale reservoirs (
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Here we present an optimized self-shielded coplanar capacitive sensor design and automated control system to provide submillimeter fluid-height resolution (∼250 μm) and control of small-scale open reservoirs without the need for direct fluid contact. Results from testing and validation of our optimized sensor and system also suggest that accurate fluid height information can be used to robustly characterize, calibrate and dynamically control a range of microfluidic systems with complex pumping mechanisms, even in cell culture conditions. Capacitive sensing technology provides a scalable and cost-effective way to enable continuous monitoring and closed-loop feedback control of fluid volumes in small-scale gravity-dominated wells in a variety of microfluidic applications. 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title Closed-loop feedback control for microfluidic systems through automated capacitive fluid height sensingElectronic supplementary information (ESI) available. See DOI: 10.1039/c7lc01223c
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