Black rice anthocyanin-rich extract and rosmarinic acid, alone and in combination, protect against DSS-induced colitis in mice

The aim of this study was to investigate the effect of black rice anthocyanin-rich extract (BRAE) and rosmarinic acid (RA), alone and in combination, on dextran sulfate sodium (DSS)-induced colitis in mice. Results showed that administration of BRAE and RA, alone and in combination, significantly de...

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Veröffentlicht in:	Food & function 2018-05, Vol.9 (5), p.2796-288
Hauptverfasser:	Zhao, Lei, Zhang, Yali, Liu, Guorong, Hao, Shuai, Wang, Chengtao, Wang, Yong
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anthocyanins - administration & dosage Cinnamates - administration & dosage Colitis Colitis - chemically induced Colitis - drug therapy Colitis - genetics Colitis - immunology Colon Cyclooxygenase 2 - genetics Cyclooxygenase 2 - immunology Cyclooxygenase-2 Depsides - administration & dosage Dextran Dextran sulfate Dextran Sulfate - adverse effects Diet Disease control Drug Therapy, Combination Female Gene expression Humans Inflammatory bowel disease Inflammatory bowel diseases Interleukin 6 Interleukin-1beta - genetics Interleukin-1beta - immunology Interleukin-6 - genetics Interleukin-6 - immunology Intestine Mice Mice, Inbred C57BL NF-kappa B - genetics NF-kappa B - immunology Nitric oxide Nitric Oxide - immunology Nitric Oxide Synthase Type II - genetics Nitric Oxide Synthase Type II - immunology Nitric-oxide synthase Oryza - chemistry Peroxidase Peroxidase - genetics Peroxidase - immunology Plant Extracts - administration & dosage Rodents Rosmarinic Acid Sodium Sulfates Tumor necrosis factor-TNF Tumor necrosis factor-α
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