Gold-catalyzed domino cyclization-alkynylation reactions with EBX reagents: new insights into the reaction mechanismElectronic supplementary information (ESI) available: Details of computational methods and experimental procedures. See DOI: 10.1039/c7dt03154h
Gold-catalyzed domino processes constitute a useful alternative to C-H functionalization for the synthesis of functionalized (hetero)arenes. Herein, we report computational studies on the gold-catalyzed cyclization alkynylation of keto-allenes with ethynylbenziodoxole (EBX) reagents, which identifie...
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| creator | Ghari, Hossein Li, Yifan Roohzadeh, Roohollah Caramenti, Paola Waser, Jerome Ariafard, Alireza |
| description | Gold-catalyzed domino processes constitute a useful alternative to C-H functionalization for the synthesis of functionalized (hetero)arenes. Herein, we report computational studies on the gold-catalyzed cyclization alkynylation of keto-allenes with ethynylbenziodoxole (EBX) reagents, which identified a gold(
i
) picolinate complex as the active catalyst, giving the first mechanistic insights into this transformation.
New insights into the mechanism of gold-catalyzed domino reactions with hypervalent iodine reagents revealed by computation and confirmed by experiments. |
| doi_str_mv | 10.1039/c7dt03154h |
| format | Article |
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i
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i
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i
) picolinate complex as the active catalyst, giving the first mechanistic insights into this transformation.
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| title | Gold-catalyzed domino cyclization-alkynylation reactions with EBX reagents: new insights into the reaction mechanismElectronic supplementary information (ESI) available: Details of computational methods and experimental procedures. See DOI: 10.1039/c7dt03154h |
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