Pyrano[3,2-]julolidin-2-ones: a novel class of fluorescent probes for ratiometric detection and imaging of Hg in live cancer cells
A novel pyrano[3,2- c ]julolidin-2-one based fluorescent molecular rotor PYJO4 has been designed and developed for selective ratiometric detection, quantification and imaging of intracellular Hg 2+ in live cells. The probe operates via a Twisted Intramolecular Charge Transfer (TICT) mechanism and ex...
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| Veröffentlicht in: | Journal of materials chemistry. B, Materials for biology and medicine Materials for biology and medicine, 2016-07, Vol.4 (28), p.4934-494 |
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| Sprache: | eng |
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| container_end_page | 494 |
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| container_issue | 28 |
| container_start_page | 4934 |
| container_title | Journal of materials chemistry. B, Materials for biology and medicine |
| container_volume | 4 |
| creator | Jha, Ajay Kumar Umar, Shahida Arya, Rakesh Kumar Datta, Dipak Goel, Atul |
| description | A novel pyrano[3,2-
c
]julolidin-2-one based fluorescent molecular rotor
PYJO4
has been designed and developed for selective ratiometric detection, quantification and imaging of intracellular Hg
2+
in live cells. The probe operates
via
a Twisted Intramolecular Charge Transfer (TICT) mechanism and exhibits high selectivity and sensitivity up to 1.14 ppb.
PYJO4
coated test strips can be used to detect mercury ions in contaminated water.
A novel pyrano[3,2-
c
]julolidin-2-one based fluorescent molecular rotor
PYJO4
has been designed and developed for selective ratiometric detection, quantification and imaging of intracellular Hg
2+
in live cells. |
| doi_str_mv | 10.1039/c6tb01413e |
| format | Article |
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c
]julolidin-2-one based fluorescent molecular rotor
PYJO4
has been designed and developed for selective ratiometric detection, quantification and imaging of intracellular Hg
2+
in live cells. The probe operates
via
a Twisted Intramolecular Charge Transfer (TICT) mechanism and exhibits high selectivity and sensitivity up to 1.14 ppb.
PYJO4
coated test strips can be used to detect mercury ions in contaminated water.
A novel pyrano[3,2-
c
]julolidin-2-one based fluorescent molecular rotor
PYJO4
has been designed and developed for selective ratiometric detection, quantification and imaging of intracellular Hg
2+
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c
]julolidin-2-one based fluorescent molecular rotor
PYJO4
has been designed and developed for selective ratiometric detection, quantification and imaging of intracellular Hg
2+
in live cells. The probe operates
via
a Twisted Intramolecular Charge Transfer (TICT) mechanism and exhibits high selectivity and sensitivity up to 1.14 ppb.
PYJO4
coated test strips can be used to detect mercury ions in contaminated water.
A novel pyrano[3,2-
c
]julolidin-2-one based fluorescent molecular rotor
PYJO4
has been designed and developed for selective ratiometric detection, quantification and imaging of intracellular Hg
2+
in live cells.</description><issn>2050-750X</issn><issn>2050-7518</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid/><recordid>eNpFUMFKAzEUDKJgqb14F94HGE022eyuNylqhYIeehBESjb7sqSkSUm2hV79clcUncvMHGYYhpBLzm44E82tUUPLuOQCT8ikYCWjVcnr0z_N3s7JLOcNG1FzVQs5IZ-vx6RDfBfXBf3Y7H30rnOBFjQGzHegIcQDejBe5wzRgvX7mDAbDAPsUmwxg40Jkh5c3OKQnIEOBzSjDaBDB26rexf67-yiBxfAuwOC0cFgAoPe5wtyZrXPOPvlKVk9PqzmC7p8eXqe3y9paoqByqplyLEtJRPK1rWqmGRWatuUSjfSdo1hUilVGVN12ipRMbRtiXaUteGNmJKrn9qUzXqXxl3puP6_THwBg_1g0A</recordid><startdate>20160713</startdate><enddate>20160713</enddate><creator>Jha, Ajay Kumar</creator><creator>Umar, Shahida</creator><creator>Arya, Rakesh Kumar</creator><creator>Datta, Dipak</creator><creator>Goel, Atul</creator><scope/></search><sort><creationdate>20160713</creationdate><title>Pyrano[3,2-]julolidin-2-ones: a novel class of fluorescent probes for ratiometric detection and imaging of Hg in live cancer cells</title><author>Jha, Ajay Kumar ; Umar, Shahida ; Arya, Rakesh Kumar ; Datta, Dipak ; Goel, Atul</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-r92t-47b0e1eb54036f8867040f4af956a94fd9c046667cc7daf6370efb5eff638c193</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jha, Ajay Kumar</creatorcontrib><creatorcontrib>Umar, Shahida</creatorcontrib><creatorcontrib>Arya, Rakesh Kumar</creatorcontrib><creatorcontrib>Datta, Dipak</creatorcontrib><creatorcontrib>Goel, Atul</creatorcontrib><jtitle>Journal of materials chemistry. B, Materials for biology and medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jha, Ajay Kumar</au><au>Umar, Shahida</au><au>Arya, Rakesh Kumar</au><au>Datta, Dipak</au><au>Goel, Atul</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pyrano[3,2-]julolidin-2-ones: a novel class of fluorescent probes for ratiometric detection and imaging of Hg in live cancer cells</atitle><jtitle>Journal of materials chemistry. B, Materials for biology and medicine</jtitle><date>2016-07-13</date><risdate>2016</risdate><volume>4</volume><issue>28</issue><spage>4934</spage><epage>494</epage><pages>4934-494</pages><issn>2050-750X</issn><eissn>2050-7518</eissn><abstract>A novel pyrano[3,2-
c
]julolidin-2-one based fluorescent molecular rotor
PYJO4
has been designed and developed for selective ratiometric detection, quantification and imaging of intracellular Hg
2+
in live cells. The probe operates
via
a Twisted Intramolecular Charge Transfer (TICT) mechanism and exhibits high selectivity and sensitivity up to 1.14 ppb.
PYJO4
coated test strips can be used to detect mercury ions in contaminated water.
A novel pyrano[3,2-
c
]julolidin-2-one based fluorescent molecular rotor
PYJO4
has been designed and developed for selective ratiometric detection, quantification and imaging of intracellular Hg
2+
in live cells.</abstract><doi>10.1039/c6tb01413e</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2050-750X |
| ispartof | Journal of materials chemistry. B, Materials for biology and medicine, 2016-07, Vol.4 (28), p.4934-494 |
| issn | 2050-750X 2050-7518 |
| language | eng |
| recordid | cdi_rsc_primary_c6tb01413e |
| source | Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
| title | Pyrano[3,2-]julolidin-2-ones: a novel class of fluorescent probes for ratiometric detection and imaging of Hg in live cancer cells |
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