Deoxyfluoro--trehalose (FDTre) analogues as potential PET probes for imaging mycobacterial infection

Mycobacterium tuberculosis , the etiological agent of human tuberculosis, requires the non-mammalian disaccharide trehalose for growth and virulence. Recently, detectable trehalose analogues have gained attention as probes for studying trehalose metabolism and as potential diagnostic imaging agents...

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Veröffentlicht in:Organic & biomolecular chemistry 2016-09, Vol.14 (36), p.8598-869
Hauptverfasser: Rundell, Sarah R, Wagar, Zachary L, Meints, Lisa M, Olson, Claire D, O'Neill, Mara K, Piligian, Brent F, Poston, Anne W, Hood, Robin J, Woodruff, Peter J, Swarts, Benjamin M
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