Zwitterionic BODIPYs with large stokes shift: small molecular biomarkers for live cellsElectronic supplementary information (ESI) available. CCDC 1454983 for molecule 2 and 1454984 for molecule 3. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c6cc09325f
The two first examples of zwitterionic BODIPYs have been synthesized via a simple S N -Ar methodology. The molecules exhibit excellent optical behavior, such as a large Stokes shift in solution and therefore a very intense emission, and can thus avoid self-quenching. The zwitterionic nature of the m...
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| creator | Sekhar, Adiki Raja Sariki, Santhosh Kumar Reddy, R. V. Ramana Bisai, Alakesh Sahu, Pushpendra Kumar Tomar, Raghuvir S Sankar, Jeyaraman |
| description | The two first examples of zwitterionic BODIPYs have been synthesized
via
a simple S
N
-Ar methodology. The molecules exhibit excellent optical behavior, such as a large Stokes shift in solution and therefore a very intense emission, and can thus avoid self-quenching. The zwitterionic nature of the molecules was unambiguously elucidated using single crystal XRD studies. The electronic conjugation was investigated by NMR, DFT (NICS (0)) and XRD analysis. Due to their inherent ionic nature, their enhanced solubility in aqueous conditions was exploited for their utility in bio-imaging and cell viability studies. These molecules demonstrate promising localization inside live yeast cells.
Two novel first examples of zwitterionic BODIPYs have been identified as promising imaging agents for granules inside live yeast cells. |
| doi_str_mv | 10.1039/c6cc09325f |
| format | Article |
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via
a simple S
N
-Ar methodology. The molecules exhibit excellent optical behavior, such as a large Stokes shift in solution and therefore a very intense emission, and can thus avoid self-quenching. The zwitterionic nature of the molecules was unambiguously elucidated using single crystal XRD studies. The electronic conjugation was investigated by NMR, DFT (NICS (0)) and XRD analysis. Due to their inherent ionic nature, their enhanced solubility in aqueous conditions was exploited for their utility in bio-imaging and cell viability studies. These molecules demonstrate promising localization inside live yeast cells.
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via
a simple S
N
-Ar methodology. The molecules exhibit excellent optical behavior, such as a large Stokes shift in solution and therefore a very intense emission, and can thus avoid self-quenching. The zwitterionic nature of the molecules was unambiguously elucidated using single crystal XRD studies. The electronic conjugation was investigated by NMR, DFT (NICS (0)) and XRD analysis. Due to their inherent ionic nature, their enhanced solubility in aqueous conditions was exploited for their utility in bio-imaging and cell viability studies. These molecules demonstrate promising localization inside live yeast cells.
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via
a simple S
N
-Ar methodology. The molecules exhibit excellent optical behavior, such as a large Stokes shift in solution and therefore a very intense emission, and can thus avoid self-quenching. The zwitterionic nature of the molecules was unambiguously elucidated using single crystal XRD studies. The electronic conjugation was investigated by NMR, DFT (NICS (0)) and XRD analysis. Due to their inherent ionic nature, their enhanced solubility in aqueous conditions was exploited for their utility in bio-imaging and cell viability studies. These molecules demonstrate promising localization inside live yeast cells.
Two novel first examples of zwitterionic BODIPYs have been identified as promising imaging agents for granules inside live yeast cells.</abstract><doi>10.1039/c6cc09325f</doi><tpages>4</tpages></addata></record> |
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| title | Zwitterionic BODIPYs with large stokes shift: small molecular biomarkers for live cellsElectronic supplementary information (ESI) available. CCDC 1454983 for molecule 2 and 1454984 for molecule 3. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c6cc09325f |
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