First report on bio-catalytic N-formylation of amines using ethyl formateElectronic supplementary information (ESI) available. See DOI: 10.1039/c6cc07679c

First report on bio-catalytic N-formylation of amines using ethyl formateElectronic supplementary information (ESI) available. See DOI: 10.1039/c6cc07679c

A bio-catalyzed N -formylation reaction of different amines has been developed using ethyl formate as a formylating agent. This protocol provides a facile and convenient strategy featuring mild reaction conditions, high efficacy, a broad substrate scope and recyclability of lipase. This method also...

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Hauptverfasser: Patre, Rupesh E, Mal, Sanjib, Nilkanth, Pankaj R, Ghorai, Sujit K, Deshpande, Sudhindra H, El Qacemi, Myriem, Smejkal, Tomas, Pal, Sitaram, Manjunath, Bhanu N
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creator Patre, Rupesh E
Mal, Sanjib
Nilkanth, Pankaj R
Ghorai, Sujit K
Deshpande, Sudhindra H
El Qacemi, Myriem
Smejkal, Tomas
Pal, Sitaram
Manjunath, Bhanu N
description A bio-catalyzed N -formylation reaction of different amines has been developed using ethyl formate as a formylating agent. This protocol provides a facile and convenient strategy featuring mild reaction conditions, high efficacy, a broad substrate scope and recyclability of lipase. This method also works on a large scale in high yield. A bio-catalyzed N -formylation reaction of different amines has been developed using ethyl formate as a formylating agent.
doi_str_mv 10.1039/c6cc07679c
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title First report on bio-catalytic N-formylation of amines using ethyl formateElectronic supplementary information (ESI) available. See DOI: 10.1039/c6cc07679c
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