Direct synthesis of butadiynyl-substituted pyrroles under solvent- and transition metal-free conditionsElectronic supplementary information (ESI) available. CCDC 1037920 and 1037921. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c5ra08820h
The work describes a convenient and highly efficient C-H butadiynylation of substituted pyrroles with the use of 1-halobutadiynes. The method requires only a simple grinding of substrates in a mortar under mild, solvent- and transition metal-free conditions and constitutes the first example of pyrro...
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