Stereocontrolled synthesis of rosuvastatin calcium iodine chloride-induced intramolecular cyclization

A novel, stereoselective approach towards rosuvastatin calcium from the known ( S )-homoallylic alcohol has been developed. The synthesis is highlighted by a regio- and stereocontrolled ICl-induced intramolecular cyclization of chiral homoallylic carbonate to deliver the C 6 -formyl statin side chai...

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Veröffentlicht in:	Organic & biomolecular chemistry 2016-01, Vol.14 (4), p.1363-1369
Hauptverfasser:	Xiong, Fangjun, Wang, Haifeng, Yan, Lingjie, Han, Sheng, Tao, Yuan, Wu, Yan, Chen, Fener
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