[3 + 2]-Annulations of -alkyl-3-substituted indoles with quinone monoketals catalysed by Brønsted acids

An organocatalytic dearomative [3 + 2]-annulation of N -alkyl-3-alkylindoles with quinone monoketals is developed. The reaction provides a mild and straightforward way to various benzofuro[2,3- b ]indolines of potential biological and pharmaceutical interest in moderate to good yields. Moreover, whe...

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Veröffentlicht in:Organic & biomolecular chemistry 2016-01, Vol.14 (3), p.124-13
Hauptverfasser: Chai, Zhuo, Chen, Jia-Nan, Liu, Zhen, Li, Xue-Fei, Yang, Pei-Jun, Hu, Ji-Ping, Yang, Gaosheng
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