Synthesis of novel polysubstituted N-benzyl-1H-pyrroles via a cascade reaction of alkynyl Fischer carbenes with α-imino glycine methyl estersElectronic supplementary information (ESI) available: 1H NMR, 13C NMR, IR and mass spectra. CCDC 970623. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c5ob01655j

An efficient and simple synthesis of novel and densely substituted N -benzyl-1 H -pyrroles 6a-r is described by a 1,4-addition/isomerization/ring closure/demetalation cascade process of alkynyl Fischer carbene complexes 1a-f and 2a and α-imino glycine methyl esters 3a , b , d , g , h , and k promoted with LDA. An efficient synthesis of N -benzyl-1 H -pyrroles is described by a 1,4-addition/isomerization/ring closure/demetalation process of alkynyl Fischer carbene and iminoester.