A convenient and rapid microwave-assisted synthesis of spirooxindoles in aqueous medium and their antimicrobial activities

A simple, ecofriendly and one-pot three-component aqueous phase protocol is developed for the synthesis of functionalized spirooxindole derivatives by the reaction of isatin, β-nitrostyrene and benzyl amine/α-amino acids in water under microwave irradiation. The method allows the easy construction o...

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Veröffentlicht in:New journal of chemistry 2016-01, Vol.4 (3), p.2225-2232
Hauptverfasser: Mali, Prakash R, Chandrasekhara Rao, L, Bangade, Vikas M, Shirsat, Prashishkumar K, George, Sara A, Jagadeesh babu, N, Meshram, H. M
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Sprache:eng
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