Disubstituted thiourea and urea derivatives: design, synthesis, docking studies and biological evaluation against nitric oxide synthase

The synthesis and biological evaluation of new types of N , N -disubstituted thiourea and urea derivatives as inhibitors of both neuronal nitric oxide synthase (nNOS) and inducible nitric oxide synthase (iNOS) are described. These compounds have been designed by reduction of the carbonyl group in th...

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Veröffentlicht in:	MedChemComm 2016-04, Vol.7 (4), p.667-678
Hauptverfasser:	Chayah, Mariem, Camacho, M. Encarnacin, Carrin, M. Dora, Gallo, Miguel A, Romero, Miguel, Duarte, Juan
Format:	Artikel
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