Genetic analysis of the clonal stability of Chinese hamster ovary cells for recombinant protein productionElectronic supplementary information (ESI) available. See DOI: 10.1039/c5mb00627a

Chinese hamster ovary (CHO) cells are frequently used for the production of recombinant proteins for therapeutical applications. However, the recombinant protein expression level of CHO cells may reduce during long-term culture. The physiological changes related to the stability of expression were n...

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Hauptverfasser:	Li, Hongwen, Chen, Kaiming, Wang, Zhe, Li, Dong, Lin, Jiannan, Yu, Chao, Yu, Fang, Wang, Xin, Huang, Lei, Jiang, Cizhong, Gu, Hua, Fang, Jianmin
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