Protein engineering with artificial chemical nucleasesElectronic supplementary information (ESI) available: Experimental procedures and biological evaluation studies. CCDC 1403896. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c5cc04615g

Herein we report the application of oxidative artificial chemical nucleases as novel agents for protein engineering. The complex ion [Cu(Phen) 2 (H 2 O)] 2+ (CuPhen; Phen = 1,10-phenanthroline) was applied under Fenton-type conditions against a recombinant antibody fragment specific for prostate-spe...

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Hauptverfasser:	Larragy, Ruth, Fitzgerald, Jenny, Prisecaru, Andreea, McKee, Vickie, Leonard, Paul, Kellett, Andrew
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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