Rational design and synthesis of novel 2-(substituted-2H-chromen-3-yl)-5-aryl-1H-imidazole derivatives as an anti-angiogenesis and anti-cancer agentElectronic supplementary information (ESI) available. See DOI: 10.1039/c4ra09945a

Based on earlier proven pharmacophore analogues of cancer a novel 2-(substituted-2 H -chromen-3-yl)-5-aryl-1 H -imidazoles ( 13-16 ) were rationally designed and synthesized by the reaction of chromene-3-carboxylic acids ( 10a-d ) with substituted acyl bromides in the presence of TEA followed by ref...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	Gudipudi, Gopinath, Sagurthi, Someswar R, Perugu, Shyam, Achaiah, G, David Krupadanam, G. L
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!