Multicomponent one-pot synthesis of highly-functionalized pyrrole-3-carbonitriles in aqueous medium and their computational studyElectronic supplementary information (ESI) available: Spectra of multisubstituted pyrrole derivatives 5a-j. See DOI: 10.1039/c4ob02229g
A one-pot green protocol involving four-components in aqueous medium is developed to synthesize highly-functionalized pyrroles in good yields. Two of the newly synthesized compounds were subjected to in silico analysis on the Pharm Mapper web-server and the human mitogen-activated protein kinase1 (M...
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