Effect of nano-scale curvature on the intrinsic blood coagulation systemElectronic supplementary information (ESI) available: Physical properties and scanning electron micrographs (SEM) of silica NPs, intrinsic coagulation activity after 3 h. See DOI: 10.1039/c4nr04128c

Effect of nano-scale curvature on the intrinsic blood coagulation systemElectronic supplementary information (ESI) available: Physical properties and scanning electron micrographs (SEM) of silica NPs, intrinsic coagulation activity after 3 h. See DOI: 10.1039/c4nr04128c

The intrinsic coagulation activity of silica nanoparticles strongly depends on their surface curvature. Nanoparticles with higher surface curvature do not denature blood coagulation factor XII on its surface, providing a coagulation 'silent' surface, while nanoparticles with lower surface...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Kushida, Takashi, Saha, Krishnendu, Subramani, Chandramouleeswaran, Nandwana, Vikas, Rotello, Vincent M
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 14487
container_issue 23
container_start_page 14484
container_title
container_volume 6
creator Kushida, Takashi
Saha, Krishnendu
Subramani, Chandramouleeswaran
Nandwana, Vikas
Rotello, Vincent M
description The intrinsic coagulation activity of silica nanoparticles strongly depends on their surface curvature. Nanoparticles with higher surface curvature do not denature blood coagulation factor XII on its surface, providing a coagulation 'silent' surface, while nanoparticles with lower surface curvature show denaturation and concomitant coagulation. The intrinsic coagulation activity of silica nanoparticles strongly depends on their surface curvature.
doi_str_mv 10.1039/c4nr04128c
format Article
fullrecord <record><control><sourceid>rsc</sourceid><recordid>TN_cdi_rsc_primary_c4nr04128c</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>c4nr04128c</sourcerecordid><originalsourceid>FETCH-rsc_primary_c4nr04128c3</originalsourceid><addsrcrecordid>eNqFkE1LAzEQhldRsH4dvAvjrQVb02aptlddsQe1UO9lmp10I9kkJNnC_nsjFi0IepqB94NnJssuhmwwZHxyI3LjWT4c3Yn9rDNiOetzfjs6-N7H-VF2HMI7Y-MJH_PO3nkhJYkIVoJBY_tBoCYQjd9gbDyBNRArAmWiVyYoASttbQnC4rrRGFXSQxsi1YVONd6aZAmNc5pqMhF9m6LS-vrL2i0Wsx7gBpXGlaYpzKs2laIG560jHxUFQFNCwjBGmTXQthZqJbxde3RVgO6ieO59IgelUxpe5uF6B3EXDkVUGxVbQBnJA4dqAAsieHidTeH3106zQ4k60Nl2nmSXj8Xb_VPfB7F0XtXpouWPnf-vX_2lL10p-QehuY7Q</addsrcrecordid><sourcetype>Enrichment Source</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Effect of nano-scale curvature on the intrinsic blood coagulation systemElectronic supplementary information (ESI) available: Physical properties and scanning electron micrographs (SEM) of silica NPs, intrinsic coagulation activity after 3 h. See DOI: 10.1039/c4nr04128c</title><source>Royal Society Of Chemistry Journals</source><source>Alma/SFX Local Collection</source><creator>Kushida, Takashi ; Saha, Krishnendu ; Subramani, Chandramouleeswaran ; Nandwana, Vikas ; Rotello, Vincent M</creator><creatorcontrib>Kushida, Takashi ; Saha, Krishnendu ; Subramani, Chandramouleeswaran ; Nandwana, Vikas ; Rotello, Vincent M</creatorcontrib><description>The intrinsic coagulation activity of silica nanoparticles strongly depends on their surface curvature. Nanoparticles with higher surface curvature do not denature blood coagulation factor XII on its surface, providing a coagulation 'silent' surface, while nanoparticles with lower surface curvature show denaturation and concomitant coagulation. The intrinsic coagulation activity of silica nanoparticles strongly depends on their surface curvature.</description><identifier>ISSN: 2040-3364</identifier><identifier>EISSN: 2040-3372</identifier><identifier>DOI: 10.1039/c4nr04128c</identifier><language>eng</language><creationdate>2014-11</creationdate><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,27929,27930</link.rule.ids></links><search><creatorcontrib>Kushida, Takashi</creatorcontrib><creatorcontrib>Saha, Krishnendu</creatorcontrib><creatorcontrib>Subramani, Chandramouleeswaran</creatorcontrib><creatorcontrib>Nandwana, Vikas</creatorcontrib><creatorcontrib>Rotello, Vincent M</creatorcontrib><title>Effect of nano-scale curvature on the intrinsic blood coagulation systemElectronic supplementary information (ESI) available: Physical properties and scanning electron micrographs (SEM) of silica NPs, intrinsic coagulation activity after 3 h. See DOI: 10.1039/c4nr04128c</title><description>The intrinsic coagulation activity of silica nanoparticles strongly depends on their surface curvature. Nanoparticles with higher surface curvature do not denature blood coagulation factor XII on its surface, providing a coagulation 'silent' surface, while nanoparticles with lower surface curvature show denaturation and concomitant coagulation. The intrinsic coagulation activity of silica nanoparticles strongly depends on their surface curvature.</description><issn>2040-3364</issn><issn>2040-3372</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid/><recordid>eNqFkE1LAzEQhldRsH4dvAvjrQVb02aptlddsQe1UO9lmp10I9kkJNnC_nsjFi0IepqB94NnJssuhmwwZHxyI3LjWT4c3Yn9rDNiOetzfjs6-N7H-VF2HMI7Y-MJH_PO3nkhJYkIVoJBY_tBoCYQjd9gbDyBNRArAmWiVyYoASttbQnC4rrRGFXSQxsi1YVONd6aZAmNc5pqMhF9m6LS-vrL2i0Wsx7gBpXGlaYpzKs2laIG560jHxUFQFNCwjBGmTXQthZqJbxde3RVgO6ieO59IgelUxpe5uF6B3EXDkVUGxVbQBnJA4dqAAsieHidTeH3106zQ4k60Nl2nmSXj8Xb_VPfB7F0XtXpouWPnf-vX_2lL10p-QehuY7Q</recordid><startdate>20141106</startdate><enddate>20141106</enddate><creator>Kushida, Takashi</creator><creator>Saha, Krishnendu</creator><creator>Subramani, Chandramouleeswaran</creator><creator>Nandwana, Vikas</creator><creator>Rotello, Vincent M</creator><scope/></search><sort><creationdate>20141106</creationdate><title>Effect of nano-scale curvature on the intrinsic blood coagulation systemElectronic supplementary information (ESI) available: Physical properties and scanning electron micrographs (SEM) of silica NPs, intrinsic coagulation activity after 3 h. See DOI: 10.1039/c4nr04128c</title><author>Kushida, Takashi ; Saha, Krishnendu ; Subramani, Chandramouleeswaran ; Nandwana, Vikas ; Rotello, Vincent M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-rsc_primary_c4nr04128c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kushida, Takashi</creatorcontrib><creatorcontrib>Saha, Krishnendu</creatorcontrib><creatorcontrib>Subramani, Chandramouleeswaran</creatorcontrib><creatorcontrib>Nandwana, Vikas</creatorcontrib><creatorcontrib>Rotello, Vincent M</creatorcontrib></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kushida, Takashi</au><au>Saha, Krishnendu</au><au>Subramani, Chandramouleeswaran</au><au>Nandwana, Vikas</au><au>Rotello, Vincent M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of nano-scale curvature on the intrinsic blood coagulation systemElectronic supplementary information (ESI) available: Physical properties and scanning electron micrographs (SEM) of silica NPs, intrinsic coagulation activity after 3 h. See DOI: 10.1039/c4nr04128c</atitle><date>2014-11-06</date><risdate>2014</risdate><volume>6</volume><issue>23</issue><spage>14484</spage><epage>14487</epage><pages>14484-14487</pages><issn>2040-3364</issn><eissn>2040-3372</eissn><abstract>The intrinsic coagulation activity of silica nanoparticles strongly depends on their surface curvature. Nanoparticles with higher surface curvature do not denature blood coagulation factor XII on its surface, providing a coagulation 'silent' surface, while nanoparticles with lower surface curvature show denaturation and concomitant coagulation. The intrinsic coagulation activity of silica nanoparticles strongly depends on their surface curvature.</abstract><doi>10.1039/c4nr04128c</doi><tpages>4</tpages></addata></record>
fulltext fulltext
identifier ISSN: 2040-3364
ispartof
issn 2040-3364
2040-3372
language eng
recordid cdi_rsc_primary_c4nr04128c
source Royal Society Of Chemistry Journals; Alma/SFX Local Collection
title Effect of nano-scale curvature on the intrinsic blood coagulation systemElectronic supplementary information (ESI) available: Physical properties and scanning electron micrographs (SEM) of silica NPs, intrinsic coagulation activity after 3 h. See DOI: 10.1039/c4nr04128c
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-10T12%3A04%3A32IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-rsc&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effect%20of%20nano-scale%20curvature%20on%20the%20intrinsic%20blood%20coagulation%20systemElectronic%20supplementary%20information%20(ESI)%20available:%20Physical%20properties%20and%20scanning%20electron%20micrographs%20(SEM)%20of%20silica%20NPs,%20intrinsic%20coagulation%20activity%20after%203%20h.%20See%20DOI:%2010.1039/c4nr04128c&rft.au=Kushida,%20Takashi&rft.date=2014-11-06&rft.volume=6&rft.issue=23&rft.spage=14484&rft.epage=14487&rft.pages=14484-14487&rft.issn=2040-3364&rft.eissn=2040-3372&rft_id=info:doi/10.1039/c4nr04128c&rft_dat=%3Crsc%3Ec4nr04128c%3C/rsc%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true