Seeing diabetes: visual detection of glucose based on the intrinsic peroxidase-like activity of MoS2 nanosheetsElectronic supplementary information (ESI) available. See DOI: 10.1039/c4nr03393k
Molybdenum disulfide (MoS 2 ) has attracted increasing research interest recently due to its unique physical, optical and electrical properties, correlated with its 2D ultrathin atomic-layered structure. Until now, however, great efforts have focused on its applications such as lithium ion batteries...
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| creator | Lin, Tianran Zhong, Liangshuang Guo, Liangqia Fu, Fengfu Chen, Guonan |
| description | Molybdenum disulfide (MoS
2
) has attracted increasing research interest recently due to its unique physical, optical and electrical properties, correlated with its 2D ultrathin atomic-layered structure. Until now, however, great efforts have focused on its applications such as lithium ion batteries, transistors, and hydrogen evolution reactions. Herein, for the first time, MoS
2
nanosheets are discovered to possess an intrinsic peroxidase-like activity and can catalytically oxidize 3,3′,5,5′-tetramethylbenzidine (TMB) by H
2
O
2
to produce a color reaction. The catalytic activity follows the typical Michaelis-Menten kinetics and is dependent on temperature, pH, H
2
O
2
concentration, and reaction time. Based on this finding, a highly sensitive and selective colorimetric method for H
2
O
2
and glucose detection is developed and applied to detect glucose in serum samples. Moreover, a simple, inexpensive, instrument-free and portable test kit for the visual detection of glucose in normal and diabetic serum samples is constructed by utilizing agarose hydrogel as a visual detection platform.
MoS
2
nanosheets were found to possess intrinsic peroxidase-like activity and applied for the colorimetric detection of serum glucose. |
| doi_str_mv | 10.1039/c4nr03393k |
| format | Article |
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2
) has attracted increasing research interest recently due to its unique physical, optical and electrical properties, correlated with its 2D ultrathin atomic-layered structure. Until now, however, great efforts have focused on its applications such as lithium ion batteries, transistors, and hydrogen evolution reactions. Herein, for the first time, MoS
2
nanosheets are discovered to possess an intrinsic peroxidase-like activity and can catalytically oxidize 3,3′,5,5′-tetramethylbenzidine (TMB) by H
2
O
2
to produce a color reaction. The catalytic activity follows the typical Michaelis-Menten kinetics and is dependent on temperature, pH, H
2
O
2
concentration, and reaction time. Based on this finding, a highly sensitive and selective colorimetric method for H
2
O
2
and glucose detection is developed and applied to detect glucose in serum samples. Moreover, a simple, inexpensive, instrument-free and portable test kit for the visual detection of glucose in normal and diabetic serum samples is constructed by utilizing agarose hydrogel as a visual detection platform.
MoS
2
nanosheets were found to possess intrinsic peroxidase-like activity and applied for the colorimetric detection of serum glucose.</description><identifier>ISSN: 2040-3364</identifier><identifier>EISSN: 2040-3372</identifier><identifier>DOI: 10.1039/c4nr03393k</identifier><language>eng</language><creationdate>2014-09</creationdate><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids></links><search><creatorcontrib>Lin, Tianran</creatorcontrib><creatorcontrib>Zhong, Liangshuang</creatorcontrib><creatorcontrib>Guo, Liangqia</creatorcontrib><creatorcontrib>Fu, Fengfu</creatorcontrib><creatorcontrib>Chen, Guonan</creatorcontrib><title>Seeing diabetes: visual detection of glucose based on the intrinsic peroxidase-like activity of MoS2 nanosheetsElectronic supplementary information (ESI) available. See DOI: 10.1039/c4nr03393k</title><description>Molybdenum disulfide (MoS
2
) has attracted increasing research interest recently due to its unique physical, optical and electrical properties, correlated with its 2D ultrathin atomic-layered structure. Until now, however, great efforts have focused on its applications such as lithium ion batteries, transistors, and hydrogen evolution reactions. Herein, for the first time, MoS
2
nanosheets are discovered to possess an intrinsic peroxidase-like activity and can catalytically oxidize 3,3′,5,5′-tetramethylbenzidine (TMB) by H
2
O
2
to produce a color reaction. The catalytic activity follows the typical Michaelis-Menten kinetics and is dependent on temperature, pH, H
2
O
2
concentration, and reaction time. Based on this finding, a highly sensitive and selective colorimetric method for H
2
O
2
and glucose detection is developed and applied to detect glucose in serum samples. Moreover, a simple, inexpensive, instrument-free and portable test kit for the visual detection of glucose in normal and diabetic serum samples is constructed by utilizing agarose hydrogel as a visual detection platform.
MoS
2
nanosheets were found to possess intrinsic peroxidase-like activity and applied for the colorimetric detection of serum glucose.</description><issn>2040-3364</issn><issn>2040-3372</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid/><recordid>eNqFjz1PwzAQhi0EEuVjYUc6NhhS3DgqSlcIogNiCHvkJJf2qGtHPiei_46fhkEIBiSY7uO59707Ic5mcjqTKr9uMuulUrna7IlJKjOZKHWT7n_n8-xQHDG_SDnP1VxNxFuJSHYFLekaA_ICRuJBG2hj1QRyFlwHKzM0jhFqzdhC7IU1AtngyTI10KN3r9RGmBjaIOgoHCnsPqSPrkzBaut4jRi4MNHVOxtVPPS9wS3aoP0uunXOb_XnxsuiXF6BHjUZXRucQjwS7p6WC_j954k46LRhPP2Kx-L8vni-fUg8N1XvaRvNq59x9T-_-ItXfdupd_bSc1Y</recordid><startdate>20140925</startdate><enddate>20140925</enddate><creator>Lin, Tianran</creator><creator>Zhong, Liangshuang</creator><creator>Guo, Liangqia</creator><creator>Fu, Fengfu</creator><creator>Chen, Guonan</creator><scope/></search><sort><creationdate>20140925</creationdate><title>Seeing diabetes: visual detection of glucose based on the intrinsic peroxidase-like activity of MoS2 nanosheetsElectronic supplementary information (ESI) available. See DOI: 10.1039/c4nr03393k</title><author>Lin, Tianran ; Zhong, Liangshuang ; Guo, Liangqia ; Fu, Fengfu ; Chen, Guonan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-rsc_primary_c4nr03393k3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lin, Tianran</creatorcontrib><creatorcontrib>Zhong, Liangshuang</creatorcontrib><creatorcontrib>Guo, Liangqia</creatorcontrib><creatorcontrib>Fu, Fengfu</creatorcontrib><creatorcontrib>Chen, Guonan</creatorcontrib></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lin, Tianran</au><au>Zhong, Liangshuang</au><au>Guo, Liangqia</au><au>Fu, Fengfu</au><au>Chen, Guonan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Seeing diabetes: visual detection of glucose based on the intrinsic peroxidase-like activity of MoS2 nanosheetsElectronic supplementary information (ESI) available. See DOI: 10.1039/c4nr03393k</atitle><date>2014-09-25</date><risdate>2014</risdate><volume>6</volume><issue>2</issue><spage>11856</spage><epage>11862</epage><pages>11856-11862</pages><issn>2040-3364</issn><eissn>2040-3372</eissn><abstract>Molybdenum disulfide (MoS
2
) has attracted increasing research interest recently due to its unique physical, optical and electrical properties, correlated with its 2D ultrathin atomic-layered structure. Until now, however, great efforts have focused on its applications such as lithium ion batteries, transistors, and hydrogen evolution reactions. Herein, for the first time, MoS
2
nanosheets are discovered to possess an intrinsic peroxidase-like activity and can catalytically oxidize 3,3′,5,5′-tetramethylbenzidine (TMB) by H
2
O
2
to produce a color reaction. The catalytic activity follows the typical Michaelis-Menten kinetics and is dependent on temperature, pH, H
2
O
2
concentration, and reaction time. Based on this finding, a highly sensitive and selective colorimetric method for H
2
O
2
and glucose detection is developed and applied to detect glucose in serum samples. Moreover, a simple, inexpensive, instrument-free and portable test kit for the visual detection of glucose in normal and diabetic serum samples is constructed by utilizing agarose hydrogel as a visual detection platform.
MoS
2
nanosheets were found to possess intrinsic peroxidase-like activity and applied for the colorimetric detection of serum glucose.</abstract><doi>10.1039/c4nr03393k</doi><tpages>7</tpages></addata></record> |
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| source | Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
| title | Seeing diabetes: visual detection of glucose based on the intrinsic peroxidase-like activity of MoS2 nanosheetsElectronic supplementary information (ESI) available. See DOI: 10.1039/c4nr03393k |
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