Sortase A catalyzed reaction pathways: a comparative study with six SrtA variantsElectronic supplementary information (ESI) available. See DOI: 10.1039/c4cy00347k

Sortase A from Staphylococcus aureus (SrtA) has emerged as a useful enzymatic tool to covalently link proteins in a site-directed manner. Despite the proposed specificity of the SrtA-catalyzed reaction for target proteins carrying the amino acid motif LPXTG, enzymatic side reactions are frequently e...

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Hauptverfasser: Heck, Tobias, Pham, Phu-Huy, Yerlikaya, Alpaslan, Thöny-Meyer, Linda, Richter, Michael
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