A molecular view of cisplatin's mode of action: interplay with DNA bases and acquired resistanceDedicated to Professor José J. C. Teixeira-Dias, FRSC, CSci, on the occasion of his 70th birthday.Electronic supplementary information (ESI) available. See DOI: 10.1039/c4cp05183a

The interaction of the widely used anticancer drug cisplatin with DNA bases was studied by EXAFS and vibrational spectroscopy (FTIR, Raman and INS), coupled with DFT/plane-wave calculations. Detailed information was obtained on the local atomic structure around the Pt( ii ) centre, both in the cispl...

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Hauptverfasser:	Marques, M. Paula M, Gianolio, Diego, Cibin, Giannantonio, Tomkinson, John, Parker, Stewart F, Valero, Rosendo, Pedro Lopes, R, Batista de Carvalho, Luis A. E
Format:	Artikel
Sprache:	eng
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