Bioluminescent coelenterazine derivatives with imidazopyrazinone C-6 extended substitutionElectronic supplementary information (ESI) available: Detailed synthetic procedures and spectral characterization of new compounds; additional information on chemiluminescence and bioluminescence properties as noted in the text; and summarized luminescence properties. See DOI: 10.1039/c4cc06886f

Three novel coelenterazine (CTZ) derivatives with extension at the C-6 position of the imidazopyrazinone structure show significant bioluminescence emission with known renilla luciferase variants, indicating a promising method to develop CTZ derivatives with superior optical properties compared to h...

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Hauptverfasser: Nishihara, Ryo, Suzuki, Hideyuki, Hoshino, Emi, Suganuma, Sakura, Sato, Moritoshi, Saitoh, Tsuyoshi, Nishiyama, Shigeru, Iwasawa, Naoko, Citterio, Daniel, Suzuki, Koji
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creator Nishihara, Ryo
Suzuki, Hideyuki
Hoshino, Emi
Suganuma, Sakura
Sato, Moritoshi
Saitoh, Tsuyoshi
Nishiyama, Shigeru
Iwasawa, Naoko
Citterio, Daniel
Suzuki, Koji
description Three novel coelenterazine (CTZ) derivatives with extension at the C-6 position of the imidazopyrazinone structure show significant bioluminescence emission with known renilla luciferase variants, indicating a promising method to develop CTZ derivatives with superior optical properties compared to hitherto reported compounds. Coelenterazine derivatives with extended substituents show significant bioluminescence emission with known renilla luciferase variants, indicating a promising method to develop substrates with superior optical properties.
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title Bioluminescent coelenterazine derivatives with imidazopyrazinone C-6 extended substitutionElectronic supplementary information (ESI) available: Detailed synthetic procedures and spectral characterization of new compounds; additional information on chemiluminescence and bioluminescence properties as noted in the text; and summarized luminescence properties. See DOI: 10.1039/c4cc06886f
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