Phase-transition contrast nanocapsules triggered by low-intensity ultrasoundElectronic supplementary information (ESI) available. See DOI: 10.1039/c4cc04641b

Phase-transition contrast nanocapsules triggered by low-intensity ultrasoundElectronic supplementary information (ESI) available. See DOI: 10.1039/c4cc04641b

A polymeric nanocapsule encapsulated with 1,1,1,3,3-pentafluorobutane was developed, in which 2,2,3,3,4,4,4-heptafluoro-1-butyl groups were introduced to the polymer terminal for high loading of liquid fluorocarbon. In vitro experiments demonstrate that its liquid/gas-phase transition can be trigger...

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Hauptverfasser: Li, Hao, Wang, Jianhao, Wang, Ping, Zheng, Jian, Song, Fangfang, Yin, Tinghui, Zhou, Guofu, Zheng, Rongqing, Zhang, Chao
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container_issue 96
container_start_page 15163
container_title
container_volume 5
creator Li, Hao
Wang, Jianhao
Wang, Ping
Zheng, Jian
Song, Fangfang
Yin, Tinghui
Zhou, Guofu
Zheng, Rongqing
Zhang, Chao
description A polymeric nanocapsule encapsulated with 1,1,1,3,3-pentafluorobutane was developed, in which 2,2,3,3,4,4,4-heptafluoro-1-butyl groups were introduced to the polymer terminal for high loading of liquid fluorocarbon. In vitro experiments demonstrate that its liquid/gas-phase transition can be triggered by mild heating. This nanocapsule can be harnessed as a contrast agent for tumor imaging under diagnostic ultrasound. Liquid fluorocarbon-loaded polymeric nanocapsules as contrast agents could be potentially triggered by mild hyperthermia under diagnostic ultrasound for tumor imaging.
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title Phase-transition contrast nanocapsules triggered by low-intensity ultrasoundElectronic supplementary information (ESI) available. See DOI: 10.1039/c4cc04641b
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