Spermidinium closo-dodecaborate-encapsulating liposomes as efficient boron delivery vehicles for neutron capture therapyElectronic supplementary information (ESI) available: Experimental details and data. See DOI: 10.1039/c4cc04344h

Spermidinium closo-dodecaborate-encapsulating liposomes as efficient boron delivery vehicles for neutron capture therapyElectronic supplementary information (ESI) available: Experimental details and data. See DOI: 10.1039/c4cc04344h

closo -Dodecaborate-encapsulating liposomes were developed as boron delivery vehicles for neutron capture therapy. The use of spermidinium as a counter cation of closo -dodecaborates was essential not only for the preparation of high boron content liposome solutions but also for efficient boron deli...

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Hauptverfasser: Tachikawa, Shoji, Miyoshi, Tatsuro, Koganei, Hayato, El-Zaria, Mohamed E, Viñas, Clara, Suzuki, Minoru, Ono, Koji, Nakamura, Hiroyuki
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container_issue 82
container_start_page 12325
container_title
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creator Tachikawa, Shoji
Miyoshi, Tatsuro
Koganei, Hayato
El-Zaria, Mohamed E
Viñas, Clara
Suzuki, Minoru
Ono, Koji
Nakamura, Hiroyuki
description closo -Dodecaborate-encapsulating liposomes were developed as boron delivery vehicles for neutron capture therapy. The use of spermidinium as a counter cation of closo -dodecaborates was essential not only for the preparation of high boron content liposome solutions but also for efficient boron delivery to tumors. Significant anti-tumor effects and longer survivals were observed in the tumor-bearing mice treated with spermidinium closo -dodecaborate-encapsulating liposomes after thermal neutron irradiation.
doi_str_mv 10.1039/c4cc04344h
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title Spermidinium closo-dodecaborate-encapsulating liposomes as efficient boron delivery vehicles for neutron capture therapyElectronic supplementary information (ESI) available: Experimental details and data. See DOI: 10.1039/c4cc04344h
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