A macrophage uptaking near-infrared chemical probe CDnir7 for in vivo imaging of inflammationElectronic supplementary information (ESI) available: Experimental procedures, spectroscopic data, cell image data. See DOI: 10.1039/c4cc02038c
Visualization of macrophages in live animals has been of great interest for a better understanding of inflammation. We developed a near infrared (NIR) probe CDnir7 that can selectively detect macrophages and visualize inflammation in vivo using the IVIS spectrum, Fluorescence Molecular Tomography (F...
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creator | Kang, Nam-Young Park, Sung-Jin Ang, Xiao Wei Emmiline Samanta, Animesh Driessen, Wouter H. P Ntziachristos, Vasilis Vasquez, Kristine O Peterson, Jeffrey D Yun, Seong-Wook Chang, Young-Tae |
description | Visualization of macrophages in live animals has been of great interest for a better understanding of inflammation. We developed a near infrared (NIR) probe
CDnir7
that can selectively detect macrophages and visualize inflammation
in vivo
using the IVIS spectrum, Fluorescence Molecular Tomography (FMT) and Multi-Spectral Optoacoustic Tomography (MSOT).
Using DOFLA, a novel fluorescent NIR macrophages probe,
CDnir7
was developed and its
in vivo
imaging of macrophages is demonstrated in the inflammation animal model. Upon tail vein injection,
CDnir7
accesses and detects the change of macrophages with near infrared fluorescence imaging. |
doi_str_mv | 10.1039/c4cc02038c |
format | Article |
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CDnir7
that can selectively detect macrophages and visualize inflammation
in vivo
using the IVIS spectrum, Fluorescence Molecular Tomography (FMT) and Multi-Spectral Optoacoustic Tomography (MSOT).
Using DOFLA, a novel fluorescent NIR macrophages probe,
CDnir7
was developed and its
in vivo
imaging of macrophages is demonstrated in the inflammation animal model. Upon tail vein injection,
CDnir7
accesses and detects the change of macrophages with near infrared fluorescence imaging.</description><identifier>ISSN: 1359-7345</identifier><identifier>EISSN: 1364-548X</identifier><identifier>DOI: 10.1039/c4cc02038c</identifier><language>eng</language><creationdate>2014-05</creationdate><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids></links><search><creatorcontrib>Kang, Nam-Young</creatorcontrib><creatorcontrib>Park, Sung-Jin</creatorcontrib><creatorcontrib>Ang, Xiao Wei Emmiline</creatorcontrib><creatorcontrib>Samanta, Animesh</creatorcontrib><creatorcontrib>Driessen, Wouter H. P</creatorcontrib><creatorcontrib>Ntziachristos, Vasilis</creatorcontrib><creatorcontrib>Vasquez, Kristine O</creatorcontrib><creatorcontrib>Peterson, Jeffrey D</creatorcontrib><creatorcontrib>Yun, Seong-Wook</creatorcontrib><creatorcontrib>Chang, Young-Tae</creatorcontrib><title>A macrophage uptaking near-infrared chemical probe CDnir7 for in vivo imaging of inflammationElectronic supplementary information (ESI) available: Experimental procedures, spectroscopic data, cell image data. See DOI: 10.1039/c4cc02038c</title><description>Visualization of macrophages in live animals has been of great interest for a better understanding of inflammation. We developed a near infrared (NIR) probe
CDnir7
that can selectively detect macrophages and visualize inflammation
in vivo
using the IVIS spectrum, Fluorescence Molecular Tomography (FMT) and Multi-Spectral Optoacoustic Tomography (MSOT).
Using DOFLA, a novel fluorescent NIR macrophages probe,
CDnir7
was developed and its
in vivo
imaging of macrophages is demonstrated in the inflammation animal model. Upon tail vein injection,
CDnir7
accesses and detects the change of macrophages with near infrared fluorescence imaging.</description><issn>1359-7345</issn><issn>1364-548X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid/><recordid>eNqFkD1Pw0AMhk8IJEphYUcyG0hNSUhCP7aqDaITQxnYItdx0oPL3ekureA_8yNIAxIDEnixZT9-X8tCnEfhMArjyQ0lROFtGI_pQPSi-C4J0mT8fLiv00kwipP0WJx4_xK2EaXjnviYQY3kjN1gxbC1Db5KXYFmdIHUpUPHBdCGa0mowDqzZpgvtHQjKI0DqWEndwZkjdV-z5Rtq1RY19hIozPF1DijJYHfWqu4Zt2ge99Dxn0xcJWtlteAO5QK14qnkL1ZdrJDO0viYuvYD8DbTs6Tsa1igQ0OgFipzp67xhBWzLB4XE7h909OxVGJyvPZd-6Li_vsaf4QOE-5bS3b0_IfPO6Ly7_muS3K-D-NT9H9gsY</recordid><startdate>20140527</startdate><enddate>20140527</enddate><creator>Kang, Nam-Young</creator><creator>Park, Sung-Jin</creator><creator>Ang, Xiao Wei Emmiline</creator><creator>Samanta, Animesh</creator><creator>Driessen, Wouter H. P</creator><creator>Ntziachristos, Vasilis</creator><creator>Vasquez, Kristine O</creator><creator>Peterson, Jeffrey D</creator><creator>Yun, Seong-Wook</creator><creator>Chang, Young-Tae</creator><scope/></search><sort><creationdate>20140527</creationdate><title>A macrophage uptaking near-infrared chemical probe CDnir7 for in vivo imaging of inflammationElectronic supplementary information (ESI) available: Experimental procedures, spectroscopic data, cell image data. See DOI: 10.1039/c4cc02038c</title><author>Kang, Nam-Young ; Park, Sung-Jin ; Ang, Xiao Wei Emmiline ; Samanta, Animesh ; Driessen, Wouter H. P ; Ntziachristos, Vasilis ; Vasquez, Kristine O ; Peterson, Jeffrey D ; Yun, Seong-Wook ; Chang, Young-Tae</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-rsc_primary_c4cc02038c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kang, Nam-Young</creatorcontrib><creatorcontrib>Park, Sung-Jin</creatorcontrib><creatorcontrib>Ang, Xiao Wei Emmiline</creatorcontrib><creatorcontrib>Samanta, Animesh</creatorcontrib><creatorcontrib>Driessen, Wouter H. P</creatorcontrib><creatorcontrib>Ntziachristos, Vasilis</creatorcontrib><creatorcontrib>Vasquez, Kristine O</creatorcontrib><creatorcontrib>Peterson, Jeffrey D</creatorcontrib><creatorcontrib>Yun, Seong-Wook</creatorcontrib><creatorcontrib>Chang, Young-Tae</creatorcontrib></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kang, Nam-Young</au><au>Park, Sung-Jin</au><au>Ang, Xiao Wei Emmiline</au><au>Samanta, Animesh</au><au>Driessen, Wouter H. P</au><au>Ntziachristos, Vasilis</au><au>Vasquez, Kristine O</au><au>Peterson, Jeffrey D</au><au>Yun, Seong-Wook</au><au>Chang, Young-Tae</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A macrophage uptaking near-infrared chemical probe CDnir7 for in vivo imaging of inflammationElectronic supplementary information (ESI) available: Experimental procedures, spectroscopic data, cell image data. See DOI: 10.1039/c4cc02038c</atitle><date>2014-05-27</date><risdate>2014</risdate><volume>5</volume><issue>5</issue><spage>6589</spage><epage>6591</epage><pages>6589-6591</pages><issn>1359-7345</issn><eissn>1364-548X</eissn><abstract>Visualization of macrophages in live animals has been of great interest for a better understanding of inflammation. We developed a near infrared (NIR) probe
CDnir7
that can selectively detect macrophages and visualize inflammation
in vivo
using the IVIS spectrum, Fluorescence Molecular Tomography (FMT) and Multi-Spectral Optoacoustic Tomography (MSOT).
Using DOFLA, a novel fluorescent NIR macrophages probe,
CDnir7
was developed and its
in vivo
imaging of macrophages is demonstrated in the inflammation animal model. Upon tail vein injection,
CDnir7
accesses and detects the change of macrophages with near infrared fluorescence imaging.</abstract><doi>10.1039/c4cc02038c</doi><tpages>3</tpages></addata></record> |
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source | Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
title | A macrophage uptaking near-infrared chemical probe CDnir7 for in vivo imaging of inflammationElectronic supplementary information (ESI) available: Experimental procedures, spectroscopic data, cell image data. See DOI: 10.1039/c4cc02038c |
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