A macrophage uptaking near-infrared chemical probe CDnir7 for in vivo imaging of inflammationElectronic supplementary information (ESI) available: Experimental procedures, spectroscopic data, cell image data. See DOI: 10.1039/c4cc02038c

Visualization of macrophages in live animals has been of great interest for a better understanding of inflammation. We developed a near infrared (NIR) probe CDnir7 that can selectively detect macrophages and visualize inflammation in vivo using the IVIS spectrum, Fluorescence Molecular Tomography (F...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Kang, Nam-Young, Park, Sung-Jin, Ang, Xiao Wei Emmiline, Samanta, Animesh, Driessen, Wouter H. P, Ntziachristos, Vasilis, Vasquez, Kristine O, Peterson, Jeffrey D, Yun, Seong-Wook, Chang, Young-Tae
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 6591
container_issue 5
container_start_page 6589
container_title
container_volume 5
creator Kang, Nam-Young
Park, Sung-Jin
Ang, Xiao Wei Emmiline
Samanta, Animesh
Driessen, Wouter H. P
Ntziachristos, Vasilis
Vasquez, Kristine O
Peterson, Jeffrey D
Yun, Seong-Wook
Chang, Young-Tae
description Visualization of macrophages in live animals has been of great interest for a better understanding of inflammation. We developed a near infrared (NIR) probe CDnir7 that can selectively detect macrophages and visualize inflammation in vivo using the IVIS spectrum, Fluorescence Molecular Tomography (FMT) and Multi-Spectral Optoacoustic Tomography (MSOT). Using DOFLA, a novel fluorescent NIR macrophages probe, CDnir7 was developed and its in vivo imaging of macrophages is demonstrated in the inflammation animal model. Upon tail vein injection, CDnir7 accesses and detects the change of macrophages with near infrared fluorescence imaging.
doi_str_mv 10.1039/c4cc02038c
format Article
fullrecord <record><control><sourceid>rsc</sourceid><recordid>TN_cdi_rsc_primary_c4cc02038c</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>c4cc02038c</sourcerecordid><originalsourceid>FETCH-rsc_primary_c4cc02038c3</originalsourceid><addsrcrecordid>eNqFkD1Pw0AMhk8IJEphYUcyG0hNSUhCP7aqDaITQxnYItdx0oPL3ekureA_8yNIAxIDEnixZT9-X8tCnEfhMArjyQ0lROFtGI_pQPSi-C4J0mT8fLiv00kwipP0WJx4_xK2EaXjnviYQY3kjN1gxbC1Db5KXYFmdIHUpUPHBdCGa0mowDqzZpgvtHQjKI0DqWEndwZkjdV-z5Rtq1RY19hIozPF1DijJYHfWqu4Zt2ge99Dxn0xcJWtlteAO5QK14qnkL1ZdrJDO0viYuvYD8DbTs6Tsa1igQ0OgFipzp67xhBWzLB4XE7h909OxVGJyvPZd-6Li_vsaf4QOE-5bS3b0_IfPO6Ly7_muS3K-D-NT9H9gsY</addsrcrecordid><sourcetype>Enrichment Source</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>A macrophage uptaking near-infrared chemical probe CDnir7 for in vivo imaging of inflammationElectronic supplementary information (ESI) available: Experimental procedures, spectroscopic data, cell image data. See DOI: 10.1039/c4cc02038c</title><source>Royal Society Of Chemistry Journals 2008-</source><source>Alma/SFX Local Collection</source><creator>Kang, Nam-Young ; Park, Sung-Jin ; Ang, Xiao Wei Emmiline ; Samanta, Animesh ; Driessen, Wouter H. P ; Ntziachristos, Vasilis ; Vasquez, Kristine O ; Peterson, Jeffrey D ; Yun, Seong-Wook ; Chang, Young-Tae</creator><creatorcontrib>Kang, Nam-Young ; Park, Sung-Jin ; Ang, Xiao Wei Emmiline ; Samanta, Animesh ; Driessen, Wouter H. P ; Ntziachristos, Vasilis ; Vasquez, Kristine O ; Peterson, Jeffrey D ; Yun, Seong-Wook ; Chang, Young-Tae</creatorcontrib><description>Visualization of macrophages in live animals has been of great interest for a better understanding of inflammation. We developed a near infrared (NIR) probe CDnir7 that can selectively detect macrophages and visualize inflammation in vivo using the IVIS spectrum, Fluorescence Molecular Tomography (FMT) and Multi-Spectral Optoacoustic Tomography (MSOT). Using DOFLA, a novel fluorescent NIR macrophages probe, CDnir7 was developed and its in vivo imaging of macrophages is demonstrated in the inflammation animal model. Upon tail vein injection, CDnir7 accesses and detects the change of macrophages with near infrared fluorescence imaging.</description><identifier>ISSN: 1359-7345</identifier><identifier>EISSN: 1364-548X</identifier><identifier>DOI: 10.1039/c4cc02038c</identifier><language>eng</language><creationdate>2014-05</creationdate><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids></links><search><creatorcontrib>Kang, Nam-Young</creatorcontrib><creatorcontrib>Park, Sung-Jin</creatorcontrib><creatorcontrib>Ang, Xiao Wei Emmiline</creatorcontrib><creatorcontrib>Samanta, Animesh</creatorcontrib><creatorcontrib>Driessen, Wouter H. P</creatorcontrib><creatorcontrib>Ntziachristos, Vasilis</creatorcontrib><creatorcontrib>Vasquez, Kristine O</creatorcontrib><creatorcontrib>Peterson, Jeffrey D</creatorcontrib><creatorcontrib>Yun, Seong-Wook</creatorcontrib><creatorcontrib>Chang, Young-Tae</creatorcontrib><title>A macrophage uptaking near-infrared chemical probe CDnir7 for in vivo imaging of inflammationElectronic supplementary information (ESI) available: Experimental procedures, spectroscopic data, cell image data. See DOI: 10.1039/c4cc02038c</title><description>Visualization of macrophages in live animals has been of great interest for a better understanding of inflammation. We developed a near infrared (NIR) probe CDnir7 that can selectively detect macrophages and visualize inflammation in vivo using the IVIS spectrum, Fluorescence Molecular Tomography (FMT) and Multi-Spectral Optoacoustic Tomography (MSOT). Using DOFLA, a novel fluorescent NIR macrophages probe, CDnir7 was developed and its in vivo imaging of macrophages is demonstrated in the inflammation animal model. Upon tail vein injection, CDnir7 accesses and detects the change of macrophages with near infrared fluorescence imaging.</description><issn>1359-7345</issn><issn>1364-548X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid/><recordid>eNqFkD1Pw0AMhk8IJEphYUcyG0hNSUhCP7aqDaITQxnYItdx0oPL3ekureA_8yNIAxIDEnixZT9-X8tCnEfhMArjyQ0lROFtGI_pQPSi-C4J0mT8fLiv00kwipP0WJx4_xK2EaXjnviYQY3kjN1gxbC1Db5KXYFmdIHUpUPHBdCGa0mowDqzZpgvtHQjKI0DqWEndwZkjdV-z5Rtq1RY19hIozPF1DijJYHfWqu4Zt2ge99Dxn0xcJWtlteAO5QK14qnkL1ZdrJDO0viYuvYD8DbTs6Tsa1igQ0OgFipzp67xhBWzLB4XE7h909OxVGJyvPZd-6Li_vsaf4QOE-5bS3b0_IfPO6Ly7_muS3K-D-NT9H9gsY</recordid><startdate>20140527</startdate><enddate>20140527</enddate><creator>Kang, Nam-Young</creator><creator>Park, Sung-Jin</creator><creator>Ang, Xiao Wei Emmiline</creator><creator>Samanta, Animesh</creator><creator>Driessen, Wouter H. P</creator><creator>Ntziachristos, Vasilis</creator><creator>Vasquez, Kristine O</creator><creator>Peterson, Jeffrey D</creator><creator>Yun, Seong-Wook</creator><creator>Chang, Young-Tae</creator><scope/></search><sort><creationdate>20140527</creationdate><title>A macrophage uptaking near-infrared chemical probe CDnir7 for in vivo imaging of inflammationElectronic supplementary information (ESI) available: Experimental procedures, spectroscopic data, cell image data. See DOI: 10.1039/c4cc02038c</title><author>Kang, Nam-Young ; Park, Sung-Jin ; Ang, Xiao Wei Emmiline ; Samanta, Animesh ; Driessen, Wouter H. P ; Ntziachristos, Vasilis ; Vasquez, Kristine O ; Peterson, Jeffrey D ; Yun, Seong-Wook ; Chang, Young-Tae</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-rsc_primary_c4cc02038c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kang, Nam-Young</creatorcontrib><creatorcontrib>Park, Sung-Jin</creatorcontrib><creatorcontrib>Ang, Xiao Wei Emmiline</creatorcontrib><creatorcontrib>Samanta, Animesh</creatorcontrib><creatorcontrib>Driessen, Wouter H. P</creatorcontrib><creatorcontrib>Ntziachristos, Vasilis</creatorcontrib><creatorcontrib>Vasquez, Kristine O</creatorcontrib><creatorcontrib>Peterson, Jeffrey D</creatorcontrib><creatorcontrib>Yun, Seong-Wook</creatorcontrib><creatorcontrib>Chang, Young-Tae</creatorcontrib></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kang, Nam-Young</au><au>Park, Sung-Jin</au><au>Ang, Xiao Wei Emmiline</au><au>Samanta, Animesh</au><au>Driessen, Wouter H. P</au><au>Ntziachristos, Vasilis</au><au>Vasquez, Kristine O</au><au>Peterson, Jeffrey D</au><au>Yun, Seong-Wook</au><au>Chang, Young-Tae</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A macrophage uptaking near-infrared chemical probe CDnir7 for in vivo imaging of inflammationElectronic supplementary information (ESI) available: Experimental procedures, spectroscopic data, cell image data. See DOI: 10.1039/c4cc02038c</atitle><date>2014-05-27</date><risdate>2014</risdate><volume>5</volume><issue>5</issue><spage>6589</spage><epage>6591</epage><pages>6589-6591</pages><issn>1359-7345</issn><eissn>1364-548X</eissn><abstract>Visualization of macrophages in live animals has been of great interest for a better understanding of inflammation. We developed a near infrared (NIR) probe CDnir7 that can selectively detect macrophages and visualize inflammation in vivo using the IVIS spectrum, Fluorescence Molecular Tomography (FMT) and Multi-Spectral Optoacoustic Tomography (MSOT). Using DOFLA, a novel fluorescent NIR macrophages probe, CDnir7 was developed and its in vivo imaging of macrophages is demonstrated in the inflammation animal model. Upon tail vein injection, CDnir7 accesses and detects the change of macrophages with near infrared fluorescence imaging.</abstract><doi>10.1039/c4cc02038c</doi><tpages>3</tpages></addata></record>
fulltext fulltext
identifier ISSN: 1359-7345
ispartof
issn 1359-7345
1364-548X
language eng
recordid cdi_rsc_primary_c4cc02038c
source Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection
title A macrophage uptaking near-infrared chemical probe CDnir7 for in vivo imaging of inflammationElectronic supplementary information (ESI) available: Experimental procedures, spectroscopic data, cell image data. See DOI: 10.1039/c4cc02038c
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-11T13%3A54%3A35IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-rsc&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20macrophage%20uptaking%20near-infrared%20chemical%20probe%20CDnir7%20for%20in%20vivo%20imaging%20of%20inflammationElectronic%20supplementary%20information%20(ESI)%20available:%20Experimental%20procedures,%20spectroscopic%20data,%20cell%20image%20data.%20See%20DOI:%2010.1039/c4cc02038c&rft.au=Kang,%20Nam-Young&rft.date=2014-05-27&rft.volume=5&rft.issue=5&rft.spage=6589&rft.epage=6591&rft.pages=6589-6591&rft.issn=1359-7345&rft.eissn=1364-548X&rft_id=info:doi/10.1039/c4cc02038c&rft_dat=%3Crsc%3Ec4cc02038c%3C/rsc%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true