Oxidative dearomatisation: the key step of sorbicillinoid biosynthesisElectronic supplementary information (ESI) available: Containing all experimental details. See DOI: 10.1039/c3sc52911h
An FAD-dependent monooxygenase encoding gene (SorbC) was cloned from Penicillium chrysogenum E01-10/3 and expressed as a soluble protein in Escherichia coli . The enzyme efficiently performed the oxidative dearomatisation of sorbicillin and dihydrosorbicillin to give sorbicillinol and dihydrosorbici...
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