Manganese-impregnated mesoporous silica nanoparticles for signal enhancement in MRI cell labelling studiesElectronic supplementary information (ESI) available: TEM images, particle size distributions, XRD, TPR, magnetometric profiles, T1 and T2 measurements at 60 MHz over time, NMRD profiles of materials, P388 cell proliferation assay after 4 h and T1-w. MR images of P388 cells incubated with a solution of M48SNs. See DOI: 10.1039/c3nr02969g

Mesoporous silica nanoparticles (MSNs) are used in drug delivery and cell tracking applications. As Mn 2+ is already implemented as a "positive" cell contrast agent in preclinical imaging procedures (in the form of MnCl 2 for neurological studies), the introduction of Mn in the porous netw...

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Hauptverfasser: Guillet-Nicolas, Rémy, Laprise-Pelletier, Myriam, Nair, Mahesh M, Chevallier, Pascale, Lagueux, Jean, Gossuin, Yves, Laurent, Sophie, Kleitz, Freddy, Fortin, Marc-André
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Sprache:eng
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