Selective anticancer copper(ii)-mixed ligand complexes: targeting of ROS and proteasomesElectronic supplementary information (ESI) available: (i) Morphological observations of MDA-MB-231 and MCF10A cells which are untreated or treated with various concentrations of copper(ii) compounds for 24 h (Fig. S1.1-S1.5A and B); (ii) a comparison between untreated and treated MDA-MB-231 and MCF10A cells in the percentage of apoptosis after incubation with 5 μM copper(ii) complexes for 24 h by flow cytomet

Selective anticancer copper(ii)-mixed ligand complexes: targeting of ROS and proteasomesElectronic supplementary information (ESI) available: (i) Morphological observations of MDA-MB-231 and MCF10A cells which are untreated or treated with various concentrations of copper(ii) compounds for 24 h (Fig. S1.1-S1.5A and B); (ii) a comparison between untreated and treated MDA-MB-231 and MCF10A cells in the percentage of apoptosis after incubation with 5 μM copper(ii) complexes for 24 h by flow cytomet

Copper compounds can be alternatives to platinum-based anticancer drugs. This study investigated the effects of a series of ternary copper( ii ) complexes, [Cu(phen)(aa)(H 2 O)]NO 3 · x H 2 O 1-4 (phen = 1,10-phenanthroline; aa = gly ( 1 ), DL-ala ( 2 ), sar ( 3 ), C-dmg ( 4 )), on metastatic and ci...

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Hauptverfasser: Ng, Chew Hee, Kong, Siew Ming, Tiong, Yee Lian, Maah, Mohd Jamil, Sukram, Nurhazwani, Ahmad, Munirah, Khoo, Alan Soo Beng
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Sprache:eng
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