A label-free electrical assay of fibrous amyloid β based on semiconductor biosensingElectronic supplementary information (ESI) available: Experimental details. See DOI: 10.1039/c3cc49460h
We propose, as an alternative to conventional spectroscopic assays, a simple method for discriminating fibrous amyloid proteins by using a label-free semiconductor-based biosensor. The highly sensitive assay is expected to be useful for accelerating amyloid related research. Simple electrical assay...
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creator | Hideshima, Sho Kobayashi, Masumi Wada, Takeyoshi Kuroiwa, Shigeki Nakanishi, Takuya Sawamura, Naoya Asahi, Toru Osaka, Tetsuya |
description | We propose, as an alternative to conventional spectroscopic assays, a simple method for discriminating fibrous amyloid proteins by using a label-free semiconductor-based biosensor. The highly sensitive assay is expected to be useful for accelerating amyloid related research.
Simple electrical assay discriminates between fibrous and non-fibrous amyloid β (Aβ) proteins, and determines the fibrous Aβ concentration with high sensitivity. |
doi_str_mv | 10.1039/c3cc49460h |
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title | A label-free electrical assay of fibrous amyloid β based on semiconductor biosensingElectronic supplementary information (ESI) available: Experimental details. See DOI: 10.1039/c3cc49460h |
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