Synthesis of a new family of acyclic nucleoside phosphonates, analogues of TPases transition statesElectronic supplementary information (ESI) available: Copies of the relevant spectra or analyses (1H NMR, 13C NMR, 31P NMR, MS, HRMS). See DOI: 10.1039/c2ob25131k

A 6-step procedure was developed for the synthesis of a new family of acyclic nucleoside phosphonates (ANPs), PHEEPA [(2-pyrimidinyl-2-(2-hydroxyethoxy)ethyl)phosphonic acids] in overall yields ranging from 4.5% to 32%. These compounds, which possess on one side a hydroxy function and on the other s...

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Hauptverfasser:	Dayde, Bndicte, Benzaria, Samira, Pierra, Claire, Gosselin, Gilles, Surleraux, Dominique, Volle, Jean-Nol, Pirat, Jean-Luc, Virieux, David
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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