Synthesis and protein binding studies of a peptide fragment of clathrin assembly protein AP180 bearing an O-linked -N-acetylglucosaminyl-6-phosphate modificationElectronic supplementary information (ESI) available: 1H and 13C NMR spectra of novel compounds and characterisation of peptide 1, glycopeptide 2 and glycophosphopeptide 3. See DOI: 10.1039/c2ob07139h

A novel post-translational modification of threonine, - N -acetylglucosaminyl-phosphate, was recently discovered on assembly protein AP180, a protein which plays a crucial role in clathrin coated vesicle formation in synaptic vesicle endocytosis (SVE). Herein, we report studies aimed at probing the...

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Hauptverfasser: Graham, Mark E, Stone, Robin S, Robinson, Phillip J, Payne, Richard J
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Sprache:eng
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