Asymmetric synthesis of ,-diamino acid derivatives with an aziridine-, azetidine- and -lactone-skeleton via Mannich-type additions across -chloro-N-sulfinyliminesElectronic supplementary information (ESI) available. See DOI: 10.1039/c2ob06637h

The efficient asymmetric synthesis of new chiral -chloro-,-diamino acid derivatives via highly diastereoselective Mannich-type reactions of N -(diphenylmethylene) glycine esters across a chiral -chloro- N-p -toluenesulfinylimine was developed. The influence of the base, LDA or LiHMDS, used for the f...

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Hauptverfasser: Callebaut, Gert, Mangelinckx, Sven, Kiss, Lornd, Sillanp, Reijo, Flp, Ferenc, De Kimpe, Norbert
Format: Artikel
Sprache:eng
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