Synthesis and study of 2-acetyl amino-3-[4-(2-amino-5-sulfo-phenylazo)-phenyl]-propionic acid: a new class of inhibitor for hen egg white lysozyme amyloidogenesisElectronic supplementary information (ESI) available: Synthesis and characterization of compounds 1 and 2, 1H NMR, 13C NMR, Table S1, Fig. S1-2, and Fig. S1-S20. See DOI: 10.1039/c2md20236k
The compounds capable of blocking the aggregation of amyloidogenic proteins may have therapeutic potentials. We report on the synthesis of 2-acetyl amino-3-[4-(2-amino-5-sulfo-phenylazo)-phenyl]-propionic acid as an HEWL (hen egg white lysozyme) amyloid inhibitor starting from phenylalanine. The com...
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