Characterization of nickel(ii)-acylperoxo species relevant to catalytic alkane hydroxylation by nickel complex with mCPBAElectronic supplementary information (ESI) available. See DOI: 10.1039/c2dt32419a

Nickel complexes with hydrotris(pyrazolyl)borate ( = Tp R ) ligands catalyze alkane oxidation with organic peroxide meta -Cl-C 6 H 4 C(&z.dbd;O)OOH ( = m CPBA). The electronic and steric hindrance properties of Tp R affect the catalyses. The complex with an electron-withdrawing group containing a less-hindered ligand, that is, Tp Me2,Br , exhibits higher alcohol selectivity. Higher selectivity for secondary over tertiary alcohols upon oxidation of methylcyclohexane indicates that the oxygen atom transfer reaction proceeds within the coordination sphere of the nickel centers. A reaction of the catalyst precursor, dinuclear nickel( ii )-bis(μ-hydroxo) complexes, with m CPBA yields the corresponding nickel( ii )-acylperoxo species, as have been characterized by spectroscopy. Thermal decomposition of the nickel( ii )-acylperoxo species in CH 2 Cl 2 yields the corresponding nickel( ii )-chlorido complexes through Cl atom abstraction. Employment of the brominated ligand increases the thermal stability of the acylperoxo species. Kinetic isotope effects observed on decay of the nickel( ii )-acylperoxo species indicate concerted O-O breaking of the nickel-bound acylperoxide and H-abstraction from the solvent molecule. Nickel( ii )-acylperoxo complexes, which show potential for H atom abstraction from aliphatic C-H, have been successfully characterized.