A general method for detecting protease activity via gelation and its application to artificial clottingElectronic supplementary information (ESI) available: experimental data; gel rheology and morphology characterization data; control experiments. See DOI: 10.1039/c2cc31537h
A modular system for detecting protease activity via enzyme-triggered gel formation is described. Protease-specific recognition sequences are utilized to achieve enzyme specificity. Artificial blood clotting is demonstrated by activating endogenous thrombin to trigger gelation in fibrinogen-deficien...
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creator | Bremmer, Steven C Chen, Jing McNeil, Anne J Soellner, Matthew B |
description | A modular system for detecting protease activity
via
enzyme-triggered gel formation is described. Protease-specific recognition sequences are utilized to achieve enzyme specificity. Artificial blood clotting is demonstrated by activating endogenous thrombin to trigger gelation in fibrinogen-deficient blood plasma.
A modular system for detecting protease activity
via
enzyme-triggered gel formation is described. |
doi_str_mv | 10.1039/c2cc31537h |
format | Article |
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via
enzyme-triggered gel formation is described. Protease-specific recognition sequences are utilized to achieve enzyme specificity. Artificial blood clotting is demonstrated by activating endogenous thrombin to trigger gelation in fibrinogen-deficient blood plasma.
A modular system for detecting protease activity
via
enzyme-triggered gel formation is described.</description><identifier>ISSN: 1359-7345</identifier><identifier>EISSN: 1364-548X</identifier><identifier>DOI: 10.1039/c2cc31537h</identifier><language>eng</language><creationdate>2012-05</creationdate><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids></links><search><creatorcontrib>Bremmer, Steven C</creatorcontrib><creatorcontrib>Chen, Jing</creatorcontrib><creatorcontrib>McNeil, Anne J</creatorcontrib><creatorcontrib>Soellner, Matthew B</creatorcontrib><title>A general method for detecting protease activity via gelation and its application to artificial clottingElectronic supplementary information (ESI) available: experimental data; gel rheology and morphology characterization data; control experiments. See DOI: 10.1039/c2cc31537h</title><description>A modular system for detecting protease activity
via
enzyme-triggered gel formation is described. Protease-specific recognition sequences are utilized to achieve enzyme specificity. Artificial blood clotting is demonstrated by activating endogenous thrombin to trigger gelation in fibrinogen-deficient blood plasma.
A modular system for detecting protease activity
via
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via
enzyme-triggered gel formation is described. Protease-specific recognition sequences are utilized to achieve enzyme specificity. Artificial blood clotting is demonstrated by activating endogenous thrombin to trigger gelation in fibrinogen-deficient blood plasma.
A modular system for detecting protease activity
via
enzyme-triggered gel formation is described.</abstract><doi>10.1039/c2cc31537h</doi><tpages>3</tpages></addata></record> |
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title | A general method for detecting protease activity via gelation and its application to artificial clottingElectronic supplementary information (ESI) available: experimental data; gel rheology and morphology characterization data; control experiments. See DOI: 10.1039/c2cc31537h |
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