Hemin/G-quadruplex simultaneously acts as NADH oxidase and HRP-mimicking DNAzyme for simple, sensitive pseudobienzyme electrochemical detection of thrombinElectronic supplementary information (ESI) available: Analytical properties of hemin/G-quadruplex assembled aptasensors for thrombin detection, experimental section, hemin/G-quadruplex electrocatalyst kinetics, the amplification of AuTHAu nanoparticles, optimization of detection conditions, and comparisons of proposed aptasensors with other de
For the first time, hemin/G-quadruplex was employed to simultaneously serve as NADH oxidase and an HRP-mimicking DNAzyme for constructing a simple and sensitive pseudobienzyme-amplifying electrochemical aptasensor for thrombin detection. Illustration of the stepwise preparation of a pseudobienzyme e...
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| creator | Yuan, Yali Yuan, Ruo Chai, Yaqin Zhuo, Ying Ye, Xiaoya Gan, Xianxue Bai, Lijuan |
| description | For the first time, hemin/G-quadruplex was employed to simultaneously serve as NADH oxidase and an HRP-mimicking DNAzyme for constructing a simple and sensitive pseudobienzyme-amplifying electrochemical aptasensor for thrombin detection.
Illustration of the stepwise preparation of a pseudobienzyme electrochemical aptasensor and the bioelectrocatalytic principle of hemin/G-quadruplex structure. |
| doi_str_mv | 10.1039/c2cc31423a |
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| source | Royal Society Of Chemistry Journals; Alma/SFX Local Collection |
| title | Hemin/G-quadruplex simultaneously acts as NADH oxidase and HRP-mimicking DNAzyme for simple, sensitive pseudobienzyme electrochemical detection of thrombinElectronic supplementary information (ESI) available: Analytical properties of hemin/G-quadruplex assembled aptasensors for thrombin detection, experimental section, hemin/G-quadruplex electrocatalyst kinetics, the amplification of AuTHAu nanoparticles, optimization of detection conditions, and comparisons of proposed aptasensors with other de |
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