Diarylprolinol in an asymmetric aldol reaction of an -alkyl--oxo aldehyde as an electrophileThis article is part of the joint ChemCommOrganic & Biomolecular Chemistry Organocatalysis web themed issue.Electronic supplementary information (ESI) available. See DOI: 10.1039/c2cc31230a

The direct aldol reaction of an -alkyl--oxo aldehyde was catalyzed by trifluoromethyl-substituted diarylprolinol 1 to afford a -oxo--hydroxy--substituted aldehyde in good yield with excellent anti -selectivity and excellent enantioselectivity. The direct aldol reaction of an -alkyl--oxo aldehyde was...

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Hauptverfasser:	Hayashi, Yujiro, Yasui, Yusuke, Kojima, Masahiro, Kawamura, Tsuyoshi, Ishikawa, Hayato
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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