Site-selective modification of proteins for the synthesis of structurally defined multivalent scaffoldsThis article is part of the ChemComm Glycochemistry and glycobiology web themed issue.Electronic supplementary information (ESI) available: Brief outline of the synthesis, MALDI-spectra. See DOI: 10.1039/c1cc16039g

A combination of classical site-directed mutagenesis, genetic code engineering and bioorthogonal reactions delivered a chemically modified barstar protein with one or four carbohydrates installed at specific residues. These protein conjugates were employed in multivalent binding studies, which suppo...

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Hauptverfasser:	Artner, Lukas M, Merkel, Lars, Bohlke, Nina, Beceren-Braun, Figen, Weise, Christoph, Dernedde, Jens, Budisa, Nediljko, Hackenberger, Christian P. R
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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