Convergent assembly of structurally diverse quinazolinesElectronic supplementary information (ESI) available: Detailed experimental procedures, analytical and spectroscopic data for representative compounds. CCDC reference number 781796. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c0ob00608d

A convergent and versatile Vilsmeier-Haack-based carbo-annulation strategy that exhibits an unusually elevated bond-forming efficiency has been developed. By virtue of its innovative approach, structure economy and simple execution conditions the methodology reported here constitutes a very attracti...

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Hauptverfasser: Crespo, Abel, Coelho, Alberto, Diz, Paula M, Fernández, Franco, Novoa de Armas, Hector, Sotelo, Eddy
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creator Crespo, Abel
Coelho, Alberto
Diz, Paula M
Fernández, Franco
Novoa de Armas, Hector
Sotelo, Eddy
description A convergent and versatile Vilsmeier-Haack-based carbo-annulation strategy that exhibits an unusually elevated bond-forming efficiency has been developed. By virtue of its innovative approach, structure economy and simple execution conditions the methodology reported here constitutes a very attractive protocol that enables the rapid assembly of structurally diverse quinazoline chemotypes. Versatile Vilsmeier-Haack-based quinazoline synthesis.
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title Convergent assembly of structurally diverse quinazolinesElectronic supplementary information (ESI) available: Detailed experimental procedures, analytical and spectroscopic data for representative compounds. CCDC reference number 781796. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c0ob00608d
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