Potential photoactivated metallopharmaceuticals: from active molecules to supported drugs

Apart from cisplatin and some derivatives successful metallopharmaceuticals are still scarce in antitumour therapy. Although novel metal complexes have been investigated in preclinical settings several promising compounds failed in different phases. With the rise of new anticancer compounds new acti...

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Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2010-09, Vol.46 (36), p.6651-6662
Hauptverfasser:	Crespy, Daniel, Landfester, Katharina, Schubert, Ulrich S, Schiller, Alexander
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - chemistry Antineoplastic Agents - therapeutic use Coordination Complexes - chemistry Coordination Complexes - therapeutic use DNA - chemistry Humans Nanoparticles - chemistry Neoplasms - drug therapy Pharmaceutical Preparations - chemistry Photosensitizing Agents - chemistry Photosensitizing Agents - therapeutic use Prodrugs - chemistry Prodrugs - therapeutic use
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