Novel helical foldamers: organized heterogeneous backbone folding in 1 : 1 α/nucleoside-derived-β-amino acid sequencesThe work has been dedicated to Dr J. S. Yadav on his 60th birthday.Electronic supplementary information (ESI) available: Synthesis, NMR Experimental, MD and DFT data. See DOI: 10.1039/c0cc01724h

Secondary structural conformation of hybrid oligo-peptides comprised of 1 : 1 alternating Nucleoside Derived β-Amino acid (NDA) and l -amino acid residues has been reported. The studies reveal that the NDA residues organize the heterogeneous backbone featuring the surface properties of both nucleic...

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Hauptverfasser: Chandrasekhar, Srivari, Kiranmai, Nayani, Kiran, Marelli Udaya, Devi, Ambure Sharada, Reddy, Gangireddy Pavan Kumar, Idris, Mohammed, Jagadeesh, Bharatam
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creator Chandrasekhar, Srivari
Kiranmai, Nayani
Kiran, Marelli Udaya
Devi, Ambure Sharada
Reddy, Gangireddy Pavan Kumar
Idris, Mohammed
Jagadeesh, Bharatam
description Secondary structural conformation of hybrid oligo-peptides comprised of 1 : 1 alternating Nucleoside Derived β-Amino acid (NDA) and l -amino acid residues has been reported. The studies reveal that the NDA residues organize the heterogeneous backbone featuring the surface properties of both nucleic acids and peptides, to adopt a novel 11/8-helical fold. The backbone in hybrid oligo-peptides comprised of 1 : 1 alternating Nucleoside Derived β-Amino acid (NDA) and l -amino acid residues adopts a novel 11/8-helical fold.
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title Novel helical foldamers: organized heterogeneous backbone folding in 1 : 1 α/nucleoside-derived-β-amino acid sequencesThe work has been dedicated to Dr J. S. Yadav on his 60th birthday.Electronic supplementary information (ESI) available: Synthesis, NMR Experimental, MD and DFT data. See DOI: 10.1039/c0cc01724h
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